EFFECTS OF THE AURORA KINASE INHIBITORS AZD1152-HQPA AND ZM447439 ON GROWTH ARREST AND POLYPLOIDY IN ACUTE MYELOID LEUKEMIA CELL LINES AND PRIMARY BLASTS

Background Aurora kinases play an essential role in the orchestration of chromosome separation and cytokinesis during mitosis.Small-molecule inhibition of the aurora kinases has been shown to result in inhibition of cell division, phosphorylation of histone H3 and the induction of apoptosis in a number of color touch 7/97 cell systems.These charact

Studies were carried out in southern Poland old fashioned cut rock candy during 2002-2006 in Scots pine stands under the effect of an outbreak of pine shoot beetles.The qualitative aspects of beetle feeding in tree crowns, studied on the basis of fallen shoots collected on experimental plots, are presented in this paper.The beetle numbers affected

The research aims to determine of herpetofauna in Regional Germplasm Preservation, PT.Bumi Mekar Hijau, Ogan Komering Ilir Regency, South Sumatra.The research was conducted maison alhambra libbra in May until June 2015, conducted on 4 transect observation purposively determined by considering the type of habitat herpetofauna and the results of a pr

Queer identities have predominantly existed at the peripheries of media representation as well as communication research.Linking this research gap with the field of video games as a medium, this study examines video game companies and their strategic communication efforts toward LGBTQ+ stakeholders through critical discourse analysis with influence